Defining asthma in epidemiological studies

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Defining asthma in epidemiological studies.

It has been suggested that, in epidemiological studies, asthma should be defined as symptomatic bronchial hyperresponsiveness (BHR). This paper critically examines the validity of this and alternative methods of defining asthma by reviewing population-based studies validating BHR and symptom questionnaires against asthma defined on the basis of a clinical assessment. It is emphasized that a sin...

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Domestic endotoxin exposure and asthma in children: epidemiological studies.

Homes contain low but measurable concentrations of endotoxin that have been linked to household conditions such as the presence of animals, smoking, crowding, and farm living. While endotoxin exposure in early life appears to have a protective effect for childhood asthma; the evidence from prospective cohort studies of young children suggests that endotoxin exposure contributes to early develop...

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Operational definitions of asthma in recent epidemiological studies are inconsistent

OBJECTIVE The best combination of questions to define asthma in epidemiological asthma studies is not known. We summarized the operational definitions of asthma used in prevalence studies and empirically assess how asthma prevalence estimates vary depending on the definition used. METHODS We searched the Thomson Reuters ISI Web of knowledge and included (1) cross-sectional studies (2) on asth...

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A review of epidemiological studies of asthma in Ghana.

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 1999

ISSN: 0903-1936,1399-3003

DOI: 10.1034/j.1399-3003.1999.14d37.x